Dr. Ashok K. Shetty

Dr. Ashok K. Shetty is Associate Director of the Institute for Regenerative Medicine, Texas A&M University College of Medicine, College Station, Texas, USA. He is also Director of Neurosciences at the Institute for Regenerative Medicine and Professor in the Department of Molecular and Cellular Medicine, Texas A&M Health Science Center College of Medicine. Dr. Shetty received his M.S. degree in human anatomy from the Kasturba Medical College Manipal of Mysore University. He obtained his Ph.D. degree in neuroscience from the All India Institute of Medical Sciences, New Delhi. Following his postdoctoral research work at Montana State University and Duke University, Dr. Shetty joined the Division of Neurosurgery (Department of Surgery) at the Duke University Medical Center as an Assistant Professor in 1995. He became an Associate Professor in 1999 and held the position of Professor from 2004 to 2011. Dr. Shetty joined the faculty at Texas A&M University Health Science Center in July 2011.

Dr. Shetty’s laboratory is interested in developing clinically applicable strategies that are efficacious for enhancing brain function after injury, disease or aging. The central areas of investigation include the following: (1) Examining the potential of stem cell-derived extracellular vesicles (EVs) for easing neuroinflammation, neurodegeneration and cognitive and mood dysfunction in prototypes of traumatic brain injury (TBI), Status Epilepticus (SE), Temporal Lobe Epilepsy (TLE) and Alzheimer’s disease (AD). (2) Studying mechanisms of brain dysfunction in prototypes of Gulf War Illness and developing treatment strategies to ease oxidative stress, neuroinflammation, and cognitive and mood impairments in Gulf War Illness. (3) Elucidating mechanisms by which transplanted neural stem cells (NSCs) and GABA-ergic progenitor cells derived from embryonic, postnatal and adult brain tissues or human induced pluripotent stem cells (hiPSCs) promote brain repair and ease spontaneous seizures and/or cognitive and mood dysfunction in prototypes of SE, TLE, and AD. (4) Developing clinically feasible strategies for improving hippocampus neurogenesis, and memory and mood function in aging and neurological diseases via stimulation of endogenous neural stem/progenitor cells.

Dr. Shetty has received continuous extramural research funding as Principal Investigator for over 23 years from sources such as the National Institutes of Health, Department of Defense, and Department of Veterans Affairs. These include 5 R01 grant awards and an R21 grant award from the National Institutes of Health (National Institute of Neurological Disorders and Stroke [NINDS], National Institute for Aging [NIA], and National Center for Complementary and Alternative Medicine [NCCAM]), 6 Peer-Reviewed Congressionally Directed Medical Research Program (CDMRP) grant awards from the Department of Defense, and 5 Merit Review grant awards and 2 Research Career Scientist Awards from the Department of Veterans Affairs.

Dr. Shetty's current research is funded by grants from the NIH and DOD. Dr. Shetty has authored 152 publications (127 as Senior or First author) and his work has appeared in many top-class journals including Molecular Psychiatry, Journal of Extracellular Vesicles, Proceedings of the National Academy of Sciences (PNAS, USA), Neuropsychopharmacology, Journal of Neuroscience, Stem Cells, Aging Cell, Progress in Neurobiology, Neuroscience and Biobehavioral Reviews, Pharmacology and Therapeutics, Neurobiology of Aging, Neurobiology of Disease, Experimental Neurology, Neurotherapeutics, Stem Cells Translational Medicine, Epilepsia, and Nature Scientific Reports. Dr. Shetty has received over 11,200 citations (with an h-index of 56) for his published research articles.

Dr. Shetty has the distinction of serving on two different NIH Study Sections as a Chartered Member. These include Clinical Neuroplasticity and Neurotransmitters study section panel (Brain Disorders and Clinical Neuroscience ZRG1) from 2004-2008, and Developmental Brain Disorders study section panel (Brain Disorders and Clinical Neuroscience IRG) from 2010-2016. In addition, he has served as an ad-hoc member of over 50 other study section panels of NIH, Congressionally Directed Medical Research Program of DoD, Maryland State Stem Cell Research Fund, New York State Stem Cell Research Fund and Henry M. Jackson Foundation Regenerative Medicine Program of NIH and DoD. He has also served as a reviewer of grant applications for over 12 international funding agencies from Germany, France, England, Israel, India, and Singapore. Dr. Shetty is Co-Editor-in-Chief of "Aging & Disease," and Associate Editor of "Frontiers in Epilepsy," "Frontiers in Neuroscience," Frontiers in Molecular Neuroscience," "Frontiers in Aging Neuroscience," and "Molecular and Cellular Epilepsy." Dr. Shetty also serves as an Editorial Board Member of many international journals, which include "Stem Cells," "Aging Cell," and "Cell Transplantation."

RESEARCH FUNDING (As Principal Investigator):

(1) Principal Investigator, Congressionally Directed Gulf war illness Research Program (Dept of Defense) Grant, Tracking Neuroinflammation in GWI from Brain-Derived Extracellular Vesicles in the Blood (2020-2023)

(2) Principal Investigator, Congressionally Directed Gulf war illness Research Program (Dept of Defense) Grant, Treating Gulf War Illness via Modulation of Leukotriene Signaling (2019-2022)

(3) Principal Investigator, National Institute of Neurological Disorders and Stroke (NIH) R01 grant, R01 NS106907-01, Mesenchymal Stem Cell-Derived A-1 Exosomes for Traumatic Brain Injury (2018-2023)

(4) Principal Investigator, Congressionally Directed Gulf war illness Research Program (Dept of Defense) Grant, Melatonin for Reversing Brain Dysfunction in Gulf War Illness (2017-2020)

(5) Principal Investigator, Congressionally Directed Gulf war illness Research Program (Dept of Defense) Grant, Curcumin nanoparticle therapy for Gulf war illness (2016-2020)

(6) Principal Investigator, Department of Veterans Affairs Merit Review Grant, Combined NSC Grafting and Neurogenic Drug Therapy for Temporal Lobe Epilepsy (2015-2018)

(7) Principal Investigator, Congressionally Directed Peer-Reviewed Medical Research Program (Dept of Defense) Grant, Human iPSC-derived GABA-ergic Precursor Cell Therapy for Chronic Epilepsy
(2014-2018)

(8) Principal Investigator, Congressionally Directed Gulf war illness Research Program (Dept of Defense) Grant, Monosodium Luminol for Improving Brain Function in Gulf War Illness (2014-2018)

(9) Research Career Scientist Award, Department of Veterans Affairs Grant, competitively renewed. (2016-2018)

(10) Principal Investigator, Department of Veterans Affairs Merit Review Grant, Memory and Mood Enhancing Strategies for Gulf War Illness (2012-2016)

(11) Research Career Scientist Award, Department of Veterans Affairs Grant (2011-2016)

(12) Principal Investigator, NIH-NCCAM Grant R21AT006256-01, Resveratrol for Enhancing Neurogenesis & Cognitive Function in the Aged (2011-2014)

(13) Principal Investigator, NIH-NINDS Grant RO1NS0054780-01, Neural Grafts and injury-induced Hippocampal Dysfunction (2006-2012)

(14) Principal Investigator, VA Merit Award, Susceptibility and Neuroprotection of Aged Hippocampus after Epileptic Seizures (2007-2011)

(15) Principal Investigator, VA Merit Award, Behavior of Stem/progenitor cells in a rat model of Gulf war syndrome (2007-2010)

(16) Principal Investigator, NIH-NINDS Grant RO1NS043507-01, Repair of Chronically Injured Hippocampus by Grafts (2003-2008)

(17) Principal Investigator, NIH-NIA Grant 1RO1AG-20924-01, Behavior of Stem Cells in the Lesioned Aging Hippocampus (2002-2008)

(18) Principal Investigator, VA Merit Award, Department of Veterans Affairs, Regeneration and Neural Transplant Integration in Lesioned Hippocampus during Aging (1999-2004)

(19) Principal Investigator, NINDS-NIH Grant RO1NS36742-01, Synaptic Regeneration in Lesioned and Grafted Hippocampus (1997-2001)

RESEARCH FUNDING (As Co-Investigator):

(1) Co-Investigator, Congressionally Directed Gulf war illness Research Program (Dept of Defense) Grant, Cannabidiol for Improving Brain Function in Gulf War Illness. PI: M. Kodali, Department of Molecular and Cellular Medicine (2020-2023)

(2) Co-Investigator, Congressionally Directed Gulf war illness Research Program (Dept of Defense) Grant, Neurosteroid therapy for Gulf War Illness. PI: S. Reddy, Department of Neuroscience and Experimental Therapeutics (2019-2021)

(3) Co-Investigator, Congressionally Directed Gulf war illness Research Program (Dept of Defense) Grant, Mitochondrial Dysfunction and Aberrant Immune Activation in the Pathobiology of Gulf War Illness. PI: Andrew West, Department of Microbial Pathogenesis (2017-2020)

(4) Co-Investigator, Congressionally Directed Gulf war illness Research Program (Dept of Defense) Grant, Vagus nerve stimulation as a treatment strategy for Gulf war illness. PI: Lee Shapiro, Dept of Surgery (2015-2018)

(5) PI of Subaward, Congressionally Directed Gulf war illness Research Program (Dept of Defense) Grant, A Pilot RCT on the Effect of Resveratrol on Mood, Memory Deficits, Hippocampal Inflammation, and Neurogenesis in Veterans with Gulf War Illness. PI: Dena Davidson, Center of Excellence for Research on Returning War Veterans, Waco, Texas.

(6) Co-Principal Investigator, CellTex Grant, MSC-derived exosomes - Review exosome production techniques with the sponsor. PI: Darwin Prockop, IRM, Department of Molecular and Cellular Medicine (2018)

(7) Co-Investigator, CURE (Citizens United for Research in Epilepsy) Grant, The Contributions of CD74 to Acquired Epilepsy, PI: Karen Newell-Rogers and Lee Shapiro, Dept of Surgery (2015-2018)

PROFESSIONAL AFFILIATIONS

(1) Member, Society for Neuroscience, North America (SFN)

(2) Charter Member, American Society for Neural Therapy & Repair (ASNTR)

(3) Member, American Association for Advancement of Science (AAAS)

(4) Member, American Epilepsy Society (AES)

(5) Member, International Society for Stem Cell Research (ISSCR)

(6) Fellow, American Society for Neural Therapy & Repair (ASNTR), Year of election: 1998.

(7) Councilor, American Society for Neural Therapy & Repair (ASNTR), 2008-2011.

(8) Member, International Society for Extracellular Vesicles (ISEV), 2017-

INSTITUTIONAL and OTHER COMMITTEE MEMBERSHIPS (Selected)

Member, Texas A&M University College of Medicine Promotions & Tenure (P&T) Committee, 2017-present

Member, Promotions & Tenure (P&T) Committee, Department of Molecular and Cellular
Medicine, Texas A&M University College of Medicine 2019-present

Member, Graduate Student Committee for Marisa Pinson (MD PhD Candidate)
Department of Neuroscience and Experimental Therapeutics,
Texas A&M HSC College of Medicine, College Station, TX 2018-present

Member, Graduate Student Committee for Dae Chung (PhD Candidate)
Department of Neuroscience and Experimental Therapeutics,
Texas A&M HSC College of Medicine, College Station, TX 2018-present

Member, Graduate Student Committee for
Robert Sommerhalter (PhD Candidate), Department of Chemistry,
Texas A&M University, College Station, TX 2018-present

Member, Graduate Student Committee for Bryan Clossen (PhD Candidate)
Department of Neuroscience and Experimental Therapeutics,
Texas A&M HSC College of Medicine, College Station, TX 2014-2018

Member, Graduate Student Committee for Andrew Robbins
(PhD Candidate), Department of Biomedical and Mechanical Engineering,
Texas A&M University, College Station, TX 2014-2018

Graduate Faculty, Texas A&M HSC College of Medicine, Temple, TX 2012-present

Member, TAMIN Graduate Program Committee. 2017 -2018

Member, Facilities and Planning Committee, Texas A&M HSC
College of Medicine, Temple, TX 2011-2016

Member, IBC subcommittee of Central Texas Veterans Health Care System (CTVHCS) 2012-2018

Member, SRS subcommittee of Central Texas Veterans Health Care System (CTVHCS) 2016-2018

Member, Departmental Tenure Committee for Carl Gregory, PhD
(Assistant Professor), Dept of Molecular and Cellular Medicine and IRM, Temple, TX 2013
Chair, Departmental Tenure Committee for Fei Liu, PhD (Assistant Professor),
Dept of Molecular and Cellular Medicine and IRM, Temple, TX 2013

Graduate Faculty, Department of Psychology and Neuroscience,
Duke University, Durham NC, USA 2007-2011

Member, Advisory Committee, NEUROCON-2015-International Conference on 2015
Development, Degeneration and Regeneration of Neurons:
Neurochemistry to Clinical Neurology, Haldia, Midnapore, India

Member, International Scientific Program Committee, Annual Conference 2014
Of the International Society for Aging and Disease (ISOAD), Beijing, China

Member, Advisory Committee, NEUROCON-2013-International Conference on
Neurodegenerative and Neurodevelopmental Disorders: 2013
Translational Aspects, Kolkota, India

Member, Working Group on Animal Models of Gulf War Illness, for the Department of 2011
Veterans Affairs ORD document, “Strategic Plan for Gulf War Illness Research”

Member, International Scientific Committee,
International Neural Transplantation & Repair-11 meeting 2011

Member, Research & Bio-safety Committee, Veterans Administration Medical Center,
Durham, North Carolina, 27705 1997-2007

Member, Institutional Animal Care and Use Committee (IACUC),
Veterans Administration Medical Center, Durham, North Carolina, 27705 2006-2011

Member, Education Committee, American Society for Neural Therapy & Repair (ASNTR) 2008-2011

EDUCATION

Postdoctoral Research: Duke University Medical Center, Durham NC (1992-1995) and Montana State University, Bozeman, Montana (1990-1992)

Ph. D. in Neuroscience, 1990, All India Institute of Medical Sciences, New Delhi, India.

M. Sc. in Human Anatomy, 1983, Mysore University, Mysore, India.

B. Sc. in Zoology, Chemistry and Botany, 1980, Mysore University, Mysore, India.

POSITIONS HELD

Associate Director, Institute for Regenerative Medicine
Texas A&M Health Science Center College of Medicine, College Station, TX, 2016-present.

Director of Neurosciences, Institute for Regenerative Medicine Texas A&M Health Science Center College of Medicine, Temple and College Station, TX, 2011-present.

Professor, Department of Molecular and Cellular Medicine,
Texas A&M Health Science Center College of Medicine, Temple and College Station, Texas, 2011-present

Research Career Scientist, Research Service, Central Texas Veterans Health Care System, Temple, Texas, 2011-2018

Professor, Department of Surgery, Division of Neurosurgery,
Duke University Medical Center, Durham, North Carolina, 2004-2011

Medical Research Scientist, Medical Research Service, Veterans Administration Medical Center, Durham, North Carolina, 1999-2011

Associate Professor, Department of Surgery, Division of Neurosurgery, Duke University Medical Center, Durham, North Carolina, 1999-2004.

Assistant Professor, Department of Surgery, Division of Neurosurgery, Duke University Medical Center, Durham, North Carolina, 1995-1998.

Research Scientist (WOC), Medical Research Service, Veterans Administration Medical Center, Durham, North Carolina, 1992-1999.

Research Associate, Department of Surgery, Division of Neurosurgery, Duke University Medical Center, Durham, North Carolina, 1992-1995,

Postdoctoral Research Associate, Department of Biology, Neurobiology Section, Montana State University, Bozeman, Montana, 1990-1992.

Research Officer, National Neural Transplant Unit, Department of Anatomy, All India Institute of Medical Sciences, New Delhi, India, 1989-1990.

Graduate Fellow, Ph.D. Program, National Neural Transplant Unit, Dept. Anatomy, All India Institute of Medical Sciences, New Delhi, India, 1987-1990.

Senior Demonstrator, Department of Anatomy, All India Institute of Medical Sciences, New Delhi, India, 1987-1989.

Lecturer, Department of Anatomy, Kasturba Medical College, Manipal, Karnataka, India, 1983-1987.

ADDITIONAL POSITIONS:

GRADUATE FACULTY, Texas A&M Health Science Center College of Medicine, 2012-present

GRADUATE FACULTY, Department of Psychology and Neuroscience,
Duke University, Durham NC, 2007-2011

EXTERNAL EXAMINER, Neurobiology Ph.D. program, All India Institute of Medical Sciences, New Delhi, India, 2012

EXTERNAL EXAMINER, Department of Neuroscience Ph.D. program,
Rosalind Franklin University-Chicago Medical School, Chicago, USA, 2007

EXTERNAL EXAMINER, Ph.D. degree program, Manipal Academy of Higher Education, Manipal, India, 2003

EXTERNAL EXAMINER, Neurobiology Ph.D. program, All India Institute of Medical Sciences, New Delhi, India, 2001

AS REVIEWER OF GRANT APPLICATIONS (NATIONAL AND INTERNATIONAL)

(a) As MEMBER of National Institutes of Health (NIH) Study Sections (Selected):

1. Member, Center for Neuroscience and Regenerative Medicine Program (CNRM)-NIH Panel, 2018/08 ZRG1 ETTN-U (82) C, July 2018.

2. Member, Special Emphasis Panel/Scientific Review Group 2018/05 ZRG1 IFCN-N (03) M meeting. Neurotoxicology and Alcohol (NAL) study section. April 2018.

3. Member, Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (T32) program Special Emphasis Panel (ZNS1 SRB-B (58)), October 2017.

4. Member, Neural Differentiation, Plasticity and Regeneration (NDPR) study section, CSR, June 2017.

5. Member, National Institute of Neurological Disorders and Stroke F32 and K01 awards review PAR-16-458 Panel, March 2017.

6. Charter Member, Developmental Brain Disorders (DBD) study section, CSR, 2010 to 2016.

7. Charter Member, Brain Disorders and Clinical Neuroscience ZRG1 CNNT study section, 2004-2008.

8. Member, National Institute of Health CSR Special Emphasis Panel, ZRG1 MDCN-G (05), April 2015.

9. Member, P42 Special Emphasis Panel for reviewing Superfund Research Program applications, National Institute of Environmental Health Sciences (NIEHS): February 2015.

10. Member, National Institute of Neurological Disorders and Stroke (NINDS) Epilepsy P20 grants application (Epilepsy without walls program) review, April 2012.

11. Member, National Institute of Neurological Disorders and Stroke (NINDS) Epilepsy EUREKA application review (ZNS1 SRB-B [32]), December 2011.

12. Member, National Institute on Aging (NIA) IRG Study section, NIA-Neuroscience, October 2011.

13. Member, National Institute on Aging (NIA) SEP Study section, AD Genetics Warehouse, October 2011.

14. Member, ZRG1 BDCN-M 57 R, PAR-11-038: Pre-Clinical Models for Developmental Disorders, June 2011.

15. Member, ZRG1 MDCN-N (02): Molecular Neuroscience (AED), June 2010.

16. Member & Chair, IFCN-C (03) study section, May 2010.

17. Member, Developmental Brain Disorders (DBD) study section, CSR, October 2009.

18. Member, Center for Scientific Review-SEP, ZRG1 IFCNH (02), October 2009.

19. Member, Human Embryonic Stem Cell Challenge Grants, ZRG1 BDA-A (52) R, September 2009.

20. Member, ARRA Studies Involving Human Embryonic Stem Cells, ZMH1 ERB-M (A1) S, August 2009.

21. Member, ZMH1 ERB-M (01), NIMH, Studies of iPS cells from Healthy and Mental Health Patients, June 2009.

22. Member, ZRG1- MDCN-F 02, CSR-Special Emphasis Panel, March 2009.

23. Charter Member, Brain Disorders and Clinical Neuroscience ZRG1 CNNT study section, 2004-2008.

24. Member, Developmental Brain Disorders (DBD) study section, CSR, October 2008.

25. Member, Center for Scientific Review Special Emphasis Panel, ZRG1 MDCN-F, March 2007.

26. Member, Center for Scientific Review ZRG1 MDCN-A, January 2006.

27. Member, Neurological Sciences and Disorders C (NSDC-SEP) Study section of NINDS, October 2005.

28. Member, National Institute for Aging Special Emphasis Panel (NIA -SEP) on “Aging and Stem Cells”. 2004.

29. Member, B-START program, National Institute of Mental Health (NIMH), 2001.

(b) As MEMBER of Study Sections of other National Funding Agencies:

1. Member (Chair), Department of Veterans Affairs, HSR&D Gulf War Veterans' Illnesses (SPLD) Merit Review Subcommittee, September 12, 2018.

2. Member, Veterans Affairs (VA) Office of Research & Development (ORD) Special Emphasis Panel on Gulf War Research (SPLD), 05/2018

3. Member, Maryland Stem Cell Research Fund study section panel for reviewing Exploratory and Investigator-initiated Research grant applications, 03/2018

4. Member, Maryland Stem Cell Research Fund study section panel for reviewing Exploratory and Investigator-initiated Research grant applications, 03/2017

5. Member, Henry M. Jackson Foundation-Center for Neuroscience and Regenerative Medicine Program (a collaborative intramural federal research program involving DOD and NIH) study section panel, 03/2017.

6. Member, Maryland Stem Cell Research Fund study section panel for reviewing Exploratory and Investigator-initiated Research grant applications, 03/2016.

7. Member, Henry M. Jackson Foundation-Center for Neuroscience and Regenerative Medicine Program (a collaborative intramural federal research program involving DOD and NIH) study section panel, 08/2015.

8. Member, Department of Veterans Affairs panel for selection of Research Career Scientists, 01/2016.

9. Member, Department of Veterans Affairs panel for selection of Research Career Scientists, 07/2015.

10. Member, Maryland Stem Cell Research Fund study section panel for reviewing Postdoctoral Research Grant applications, 04/2015.

11. Member, Maryland Stem Cell Research Fund study section panel for reviewing Exploratory and Investigator-initiated Research grant applications, 03/2015.

12. Member, Congressionally Directed Department of Defense (DOD) Gulf War Illness Research Program study section panel, 11/2014.

13. Member, Henry M. Jackson Foundation-Center for Neuroscience and Regenerative Medicine Program (a collaborative intramural federal research program involving DOD and NIH) study section panel, 09/2014.

14. Member, Maryland Stem Cell Research Fund study section for Exploratory Research grants, 03/2014.

15. Member, New York Stem (NY-STEM) - Neural Stem Cells study section, 10/2013.

16. Member, New York Stem (NY-STEM) - Shared Facilities Panel, 07/2013

17. Member, Gulf War Illness Research Consortium Grant Applications Review Committee, Congressionally Directed Medical Research Program (CDMRP), Department of Defense, 08/2012.

18. Member, New York Stem (NY-STEM) - Neurogenesis & Neural Stem Cells study section, 2/2012.

19. Member, Maryland Stem Cell Research Fund study section for Exploratory Research grants, 03/2013.

20. Member, Maryland Stem Cell Research Fund study section for Exploratory Research grants, 03/2012.

21. Member, Maryland Stem Cell Research Fund study section for Exploratory Research grants, 03/2011.

22. Member, Maryland Stem Cell Research Fund study section for Exploratory Research grants, 03/2010.

23. Member, Maryland Stem Cell Research Fund study section for Exploratory Research grants, 03/2009.

24. Member, New York Stem (NY-STEM) - Neurogenesis & Neural Stem Cells study section, 10/2009.

25. Member, New York Stem (NY-STEM) - Neurogenesis & Neural Stem Cells study section, 10/2008.

26. Member, Maryland Stem Cell Research Fund study section for Exploratory Research grants, 03/2008.

(c) As Reviewer of Grant Proposals for National and International Funding Agencies:

1. Reviewer of Grant Proposals in the Area of Neuroscience for Science Foundation of Ireland, Ireland, 2018

2. Reviewer of Grant Proposals for Fondazione Telethon Piazza Cavour 1, Milan, Italy. May 2016

3. Reviewer of Grant Proposals for National Medical Res Council, Ministry of Health, Singapore, Feb 2016

4. Reviewer of Master’s thesis, Kuwait University, June 2016

5. Reviewer of Grant application for South Plains Foundation, 511, Avenue K, Lubbock, Texas, July 2016

6. Reviewer of Grant Proposals for Fondazione Telethon Piazza Cavour 1, Milan, Italy. May 2015

7. Reviewer of Grant Proposals for National Medical Res Council, Ministry of Health, Singapore, Jan 2014

8. Reviewer of Grant Proposals for AXA Research Fund, France. July 2012

9. Reviewer of Grant Proposals for Wellcome (UK) and Department of Biotechnology (INDIA) Alliance Grants, Biomedical Research Fellowship Program for India, January 2012

10. Reviewer of Grant Proposals for Netherlands Organization for Scientific Research. October 2011

11. Reviewer of Grant Proposals in the Area of Neural Stem Cells Israel Science Foundation, Israel Academy of Sciences and Humanities, Israel. 2010

12. Reviewer of Grant Proposals in the Area of Neurobiology of Aging for American Federation for Aging Research (AFAR), 2010

13. Reviewer of Grant Proposal in the area of Neural Stem Cells and Alzheimer’s disease for Dutch Internationale Stichting Alzheimer Onderzoek, Alzheimer Forschung Initiative e. V. Grabenstr. 5 D- 40213 Düsseldorf. 2009

14. Reviewer of Grant Proposals in the Area of Neural Stem Cells and Epilepsy for Biomedical Research Council, A*STAR, Singapore, 2005-2010

15. Reviewer of Grant Proposals in the Area of Neural Stem Cells and Adult Neurogenesis for PT-DLR Gesundheitsforschung (Programme Management Organisation for the Health Research Programme of the BMBF), Germany, 2008-2009

16. Reviewer of Grant Proposals in the Area of Neurobiology of Aging and Alzheimer’s disease for Research into Aging, Help the Aged London N1 9UZ, England, 2008

Neuroscience, Stem Cell Biology

EDITORIAL EXPERIENCE:

(a) As CO-EDITOR-IN-CHIEF:

Aging & Disease, Co-Editor-in-Chief - 2010 to present (Impact Factor: 5.4)

(b) As ASSOCIATE EDITOR:

1. Frontiers in Neuroscience, 2017 to present, (Impact Factor: 4.2)
2. Frontiers in Molecular Neuroscience, 2017 to present, (Impact Factor: 4.4)
3. Frontiers in Aging Neuroscience, 2017 to present, (Impact Factor: 4.6)
4. Frontiers in Neurology, 2012 to present, (Impact Factor: 3.2)
5. Neurogenesis, 2013 to present, (Impact Factor: N/A)
6. Neuroscience Insights, 2018 to present, (Impact Factor: N/A)

(c) As MEMBER OF THE EDITORIAL BOARD:

1. Aging Cell, Blackwell (IF: 6.6), 2008 to present, (Impact Factor: 7.6)
2. Stem Cells, Alphamed Press, 2006 to present, (Impact Factor: 6.0)
3. Frontiers in Pharmacology, 2014 to present, (Impact Factor: 4.6)
4. Cell Transplantation, 2015 to present, (Impact Factor: 3.5)
5. Stem Cells International, Hindawi, 2008 to 2016. (Impact Factor: 4.1)
6. Frontiers in Cell and Developmental Biology, (Impact Factor: 5.2)

(d) As SECTION EDITOR or GUEST EDITOR:

1. Section Editor, “Stem Cells and Aging” section of Aging Cell, 2005-2007, (Impact Factor: 7.6)
2. Guest Editor, Special issue on “Aging & Stem Cells”, Aging Cell, Dec. 2004, (Impact Factor: 7.6)

(e) As REVIEWER of manuscripts for International Journals:

Molecular Psychiatry Annals of Neurology
Journal of Extracellular Vesicles Journal of Neuroscience
Stem Cells Neurobiology of Disease
Aging Cell Epilepsia
BRAIN Behavioral Brain Research
Progress in Neurobiology Brain pathology
Hippocampus Cell Transplantation
Neurobiology of Aging Biological Psychiatry
Neuropsychopharmacology Journal of Comparative Neurology
Trends in Neurosciences European Journal of Neuroscience
Stroke BMC Neuroscience
Journal of Cellular and Molecular Med BMC Biology
GLIA Neuropharmacology
Journal of CBF & M Journal of Neurochemistry
Neuroscience Brain Research
Developmental Brain Research Restorative Neurology and Neuroscience
NeuroReport Neuroscience Letters
Neurochemistry International Acta Neuropathologica
Synapse Molecular & Cellular Neuroscience
Biotechniques International Journal of Developmental Neuroscience
Journal of Neuroscience Research Stem Cells & Development
Current Aging Science Epilepsy & Behavior
Journal of Neurobiology Developmental Neurobiology
Journal of Neurotrauma Brain Research Bulletin
Epilepsy Research Stem Cells & Cloning
Neurosci and Biobehavioral Reviews Development
Nature Communications Scientific Reports
Hypertension Frontiers in Molecular Neuroscience
Experimental Neurology

HONORS AND AWARDS

1. Chair of the symposium:"Stem Cells in Aging and Disease" on October 6, 2018, at the Annual Conference of the International Society for Aging and Disease (ISOAD), October 5-8, Nice, France.

2. Chair of the symposium:"Precision Medicine and Technological Challenges in Neuroscience and
Epileptology" on September 20, 2018, at the International Neuroscience Conference, Ribeirao Preto School of Medicine, University of Sao Paulo, Brazil, September 18-21, Ribeiro Preto, Brazil.

3. Chair of VA Study Section panel: 2018 HSR&D Gulf War Veterans' Illnesses (SPLD) Merit Review Subcommittee, September 12, 2018.

4. Research Career Scientist Award, Department of Veterans Affairs, 2016-2018.

5. Research Career Scientist Award, Department of Veterans Affairs, 2011-2016.

6. "Director's Award of Excellence", Central Texas Veterans Health Care System (CTVHCS), 2012.

7. Highly Cited Scientist - Among the top 1% of scientists worldwide in the field of Neuroscience and Behavior, in terms of total citations received for published articles in consecutive 10-year periods, Essential Science Indicators of THOMPSON REUTERS. Has been a member of this list from 2009 to 2016.

8. Author of a Highly Cited Paper - Among the top 1% of articles published worldwide in all fields over 10-year period, in terms of the total citations received for the article, Essential Science Indicators of THOMPSON REUTERS. Has been a member of this list from 2009 to 2016.

9. Chair of the symposium, “Stem Cells in Aging and Disease” at the Annual Conference of the International Society for Aging and Disease (ISOAD), October 2016, Stanford University, Stanford, CA, USA.

10. Chair of the symposium, "Stem Cells, Aging and Disease" on November 1, 2014, at the Annual Conference of the International Society for Aging and Disease (ISOAD), October 31-November 3, Beijing, China.

11. Member, International Scientific Program Committee, Annual Conference of the International Society for Aging and Disease (ISOAD), October 31-November 3, 2014, Beijing, China.

12. Chair of the symposium, "Pediatric Neurorestology" on March 1, 2014, at the combined annual conference of International Association of Neurorestology (IANR), Stem Cell Society of India, and Global College of Neuroprotection and Neuroregeneration, Mumbai, India.

13. Chair of the Symposium on: Psychiatric Comorbidities and the Epilepsies II: Technological Advances and Future Perspectives. International Conference on “Epilepsies: Complexity and Co-Morbidities (Neuroscience 2013)” Ribeirao Preto School of Medicine, University of Sao Paulo, Brazil, (Sept. 2013).

14. Member of Advisory Committee, NEUROCON-2017-International Conference Neurological Disorders, 2017, Haldia, Midnapore, India.

15. Member, International Scientific Program Committee, for the Annual Conference of the International Society for Aging and Disease (ISOAD), October 2016, Stanford University, Stanford, CA.

16. International Advisory Council, IV World Congress on Geriatrics and Gerontology, November 23-25, 2016, Indian Institute of Sciences, Bengaluru, India

17. External Advisory Board Member, Arkansas National Science Foundation (NSF) EPSCoR Project for the Center for Advanced Surface Engineering (CASE), 2016-2021.

18. Member of Advisory Committee, NEUROCON-2015-International Conference on Development, Degeneration and Regeneration of Neurons: Neurochemistry to Clinical Neurology, Jan 7-10, 2015, Haldia, Midnapore, India.

19. Member of Advisory Committee, NEUROCON-2013-International Conference on Neurodegenerative and Neurodevelopmental Disorders: Translational Aspects, Kolkota, India.

20. Chair and Organizer of a Symposium on Epilepsy Therapeutics, International Neural Therapy and Research Conference (INTR-11), Clear Water Beach, FL, USA, May 2011.

21. Member, International Scientific Committee, International Neural Transplantation & Repair-11 meeting, (May 2011).

22. VA Merit Award, Department of Veterans Affairs, 2011-2015.

23. Councilor, AMERICAN SOCIETY FOR NEURAL THERAPY & REPAIR (2008-2011).

24. VA Merit Award, Department of Veterans Affairs, 2007-2011.

25. Session Chair, Stem Cells & Epilepsy, Symposium on Neuroscience & Epilepsy, Ribeirao Preto School of Medicine, University of Sao Paulo, Brazil, (Sept. 2008).

26. Member, Education Committee, American Society for Neural Therapy & Repair, 2007-2011.

27. FELLOW, AMERICAN SOCIETY FOR NEURAL THERAPY & REPAIR (Year of election: 1998).

28. VA Merit Award, Department of Veterans Affairs, 1999-2004.

29. BIOGRAPHEE, WHO’s WHO in Science and Engineering.

30. BIOGRAPHEE, WHO’s WHO in America.

31. BIOGRAPHEE, WHO’s WHO in the World.

32. T. SOMANI NEUROSCIENCE RESEARCH AWARD, Annual Conference of Indian Academy of Neurosciences, 1989.

33. INTERNATIONAL BRAIN RES. ORGANIZATION (IBRO) AWARD to attend “Intensive workshop on Basic Neuroscience” at Shangai, China, 1989.

INVITED LECTURES AND SYMPOSIA (Selected)

“Human iPSC-based therapy for Temporal lobe Epilepsy” Invited Speaker, Brain Institute of Rio Grande do Sul (BraIns), Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil, December 6, 2019.

“Stem Cell-Derived Extracellular Vesicles for Improving Brain Function in Models of TBI, SE, and Aging” Invited Speaker, Brain Institute of Rio Grande do Sul (BraIns), Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil, December 5, 2019.

Invited Speaker, Third International Conference on Stem Cells, Efficacy of Human iPSC-derived Interneuron Precursor Cell Grafts for Alleviating Spontaneous Seizures and Related Co-morbidities in a Model of Chronic Temporal Lobe Epilepsy, Chania, Greece, October 12, 2019

“Promise of Human Induced Pluripotent Stem Cell (hiPSC)-based Therapy for Epilepsy”. Invited Speaker, Clinical Science & Translational Research, TAMHSC Grand Rounds, Bryan, USA, March 5, 2019.

“Advances in stem cell therapy for epilepsy” Invited Speaker, 22nd Annual Pediatric Epilepsy Symposium, Ashville, North Carolina, USA. March 1, 2019.

“Stem Cell Therapy in Epilepsy” Invited Speaker, 12th Qatar Epilepsy Symposium, International League against epilepsy (ILAE), Hamad Medical City, Doha, Qatar. February 15, 2019.

“MSC-derived exosomes for modulating status epilepticus induced injury, neuroinflammation and cognitive dysfunction” Invited Speaker, 12th Qatar Epilepsy Symposium, International League against epilepsy (ILAE), Hamad Medical City, Doha, Qatar. February 15, 2019.

“Prospects for treating Alzheimer’s disease using MSC-derived A-1 exosomes” Invited Speaker, TAMU and King Abdullah University of Science and Technology (KAUST) symposium, College Station, USA. February 4, 2019.

“Human medial ganglionic eminence cell therapy for easing seizures and related co-morbidities in Temporal lobe Epilepsy” Invited Speaker, at the Annual Conference of the International Society for Aging and Disease (ISOAD), Nice, France. October 6, 2018.

“Exosome therapy for status epilepticus induced neuroinflammation and cognitive dysfunction, at the International Neuroscience Conference, Ribeirao Preto School of Medicine, University of Sao Paulo, Ribeiro Preto, Brazil, September 19, 2018

Promise of Human induced pluripotent stem cells for developing patient-specific cell therapy for Temporal lobe Epilepsy” Invited Speaker, University of Missouri, Columbia, MO, August 13, 2018.

“Promise of exosomes for treating neurological disorders” Invited VIP speaker, at the Annual Conference of International Association of NeuroRestology (IANR), Buenos Aires, Argentina. September 2017.

“Exosomes for easing status epilepticus induced abnormal neurogenesis” Invited VIP speaker, International Health and Anti-Aging Summit, Qingdao, China. September 2017.

“Exosomes for improving hippocampus function” Invited speaker, International Conference on “HIPPOCAMPUS, Taormina, Italy. June 14, 2017.

“Efficacy of MSC-derived extracellular vesicles for easing status epilepticus induced cognitive and memory dysfunction” Annual meeting of the International Society for Extracellular Vesicles, Toronto, Canada. May 18, 2017.

“Intranasally administered MSC-derived exosomes ease status epilepticus induced neurodegeneration, neuroinflammation and prevent cognitive and memory dysfunction” Invited speaker, Federal Drug Administration, and CellTex meeting, Mexico City, Mexico. April 21, 2017.

“Efficacy of Monosodium Luminol for treating Gulf War Illness” Invited speaker, Center of Excellence for Research on Returning Veterans, Waco TX, USA. April 18, 2017.

“Promise of hiPSC-derived GABA-ergic cell and Stem Cell-Derived Exosomes for Treating Temporal Lobe Epilepsy”, Invited speaker, MD-PhD Student Summer Seminar Series, Texas A&M College of Medicine, College Station, TX, USA. June 2017

“Promise of hiPSC-derived GABA-ergic cell and Stem Cell-Derived Exosomes for Treating Temporal Lobe Epilepsy”, MD-PhD Student Summer Seminar Series, College Station, TX, USA. July 2017

• Keynote Speaker, Arkansas Stem Cell Consortium Conference, Little Rock, Arkansas, USA. October 2016. "Promise of human-induced pluripotent stem cell-derived medial ganglionic eminence-like precursor cells for treating temporal lobe epilepsy."

• Symposium on Stem Cells in Aging and Disease, at the International Society for Aging and Disease (ISOAD) Conference, Stanford University, Stanford, CA, USA, October 2016. "Triggering neurogenesis in the injured aged hippocampus through systemic administration of FGF-2 and BDNF".

• Continuing Medical Education (CME) program and Fellowship in Stem Cell Therapies, Module IV: Clinical applications of Regenerative Therapies. Conference on Anti-Aging Medicine, Las Vegas, NV. December 2016. "Use of Neurobiologics in the Treatment of Epilepsy"

•Biology of Aging Seminar at Huffington Center on Aging, Baylor College of Medicine, Houston, Texas, March 11, 2015.“Efficacy of Resveratrol for counteracting age-related memory dysfunction”,

• “Resveratrol therapy in old age prevents memory dysfunction via pro-cognitive and anti-inflammatory effects”, Annual Conference of the International Society for Aging and Disease (ISOAD) Beijing, China, November 1, 2014.

• “Promise of induced pluripotent stem cells for treating temporal lobe epilepsy”, Seminars in Translational Neuroscience, Center for Translational Neuroscience, University of Missouri, School of Medicine, Columbia, MO, USA, September 22, 2014.

• "Efficacy of Fluoxetine and Resveratrol for Easing Cognitive and Mood Dysfunction in Gulf War Illness”, Gulf War Illness-Research Advisory Committee meeting (GWI-RAC) at the Department of Veterans Office of Research and Development, Washington DC April 2014.

• "Long-term behavioral consequences of exposure to blast shock waves”, Baylor Scott & White and TAMHSC Research Symposium on Traumatic brain injury, Temple, Texas June 2014.

• "Promise of induced pluripotent stem cell-derived precursor cells for treating epilepsy", Invited Seminar at the Neuroscience Research Group meeting of Baylor Scott & White, Texas A&M and CTVHCS neuroscience researchers. Temple, TX. March 2014.

• "GABA-ergic Cell Therapy for Chronic Temporal Lobe Epilepsy" on March 1, 2014, at the combined annual conference of International Association of Neurorestology (IANR), Stem Cell Society of India, and Global College of Neuroprotection and Neuroregeneration, Mumbai, India. March 2014.

• "Efficacy of human-induced pluripotent stem cell (hiPSC) derived neural cell grafts for easing chronic epilepsy mediated spontaneous seizures and related co-morbidities" on March 3, 2014, at the Institute of Post-Graduate Medical Education and Research, Kolkota, India. March 2014.

• “Neurogenesis and Epilepsy: Can Early Neural Stem Cell Grafting Intervention Provide Protection?” Symposium on: Psychiatric Comorbidities and the Epilepsies II: Technological Advances and Future Perspectives. International Conference, Epilepsies: Complexity and Co-Morbidities (Neuroscience 2013, Ribeirao Preto School of Medicine, University of Sao Paulo, Brazil, September 2013.

• "Promise of subventricular zone neural stem cells for easing focal injury or status epilepticus induced chronic hippocampal dysfunction". International Summer School on "Neural Stem Cells in Development and Disease" held at Levico Terme, Trento, Italy, from September 2012.

• "Hippocampal Dysfunction in an Animal Model of Gulf War Illness”, Gulf War Illness Researcher's Meeting" at the Department of Veterans, Office of Research and Development, Washington DC September 2012.

• “Prospects of Stem Cell Therapy for Temporal Lobe Epilepsy”, June 2012, Summer Seminary Series of MD Ph.D. students at the Texas A&M HSC College of Medicine, Temple, TX.

• “Advances in Neural Stem Cell Therapy for Epilepsy”, April 2012, Neuroscience Seminar Series, Department of Biology, Wesleyan University, Middletown, CT.

• “Efficacy of Cell Therapy for Easing Spontaneous Seizures and Cognitive and mood dysfunction in Temporal Lobe Epilepsy”. May 2012. Department of Molecular and Cellular Medicine seminar series, TAMHSC, College Station, TX.

• Invited symposium talk on Efficacy of fibroblast growth factor-2 for easing status epilepticus-induced chronic epilepsy and cognitive dysfunction in aged animals. March 2012, Spring Brain Conference (SBC-2012), Tucson, AZ.

• “Hippocampal Dysfunction in Gulf War illness” Invited Speaker, Waco VA, Center of Excellence. Waco, TX, August 2011.

• Introductory talk on Epilepsy Therapeutics, A symposium at International Neural Therapy and Research Conference (INTR-11), Clear Water Beach, FL, USA, May 2011.

• “Neural Progenitor Cell Therapy for Chronic Temporal Lobe Epilepsy”, A symposium on Emerging Therapies for Epilepsy and other Neurodegenerative Disorders, University of South Florida, Tampa, FL. May 2011.

• “Stem Cell Dysfunction in Gulf war illness and its implications on cognitive function and mood” Invited Speaker, Research Advisory Committee on Gulf War Illness, Department of Veterans Affairs Head Quarters, Washington DC, June 2010.

• “Efficacy of Neural Stem Cells for treating Temporal Lobe Epilepsy” Invited Speaker, Institute for Regenerative Medicine, Texas A & M University School of Medicine, Temple, TX. March 2009.

• “Neural Stem Cells and Epilepsy” Invited Speaker, Center for Brain Repair, University of South Florida, Tampa, FL. September 2008.

• “Hippocampal neurogenesis and Neural Stem Cells in chronic temporal lobe epilepsy” Invited Speaker, Symposium on Neuroscience & Epilepsy, Sao Paulo, BRAZIL, September 2008.

• “Mechanisms of Age-related Decline in Hippocampal Stem Cell Function” Invited Speaker, American Aging Association meeting at Boulder, CO, June 2008.

• “Stem Cells and Epilepsy” Invited Speaker, CME, Advances in Epilepsy Treatment, at American Epilepsy Society Meeting, Philadelphia, PA, USA December 2007

• “Neural Cell Therapy for Temporal Lobe Epilepsy” Invited Speaker, Rosalinda Franklin University School of Medicine (Chicago Medical School), Chicago. IL, USA, August 2007.

• “Hippocampal stem cells and Aging” Invited Speaker, State University of New York, Brooklyn, NY, USA, July 2007.

• “Efficacy of cell transplants for treating temporal lobe epilepsy” Invited Speaker, Fourth Conference on Epileptogenesis, Pisa, Italy, May 2007.

• “Behavior of stem cells in the aged hippocampus” Invited Speaker, Alzheimer’s disease research center, Duke University Medical Center, Durham NC, March 2007.

• “Stem/Progenitor Cells in the Aging Hippocampus” Invited Speaker, Symposium on STEM CELLS AND AGING, at Washington DC, sponsored by National Institute for Aging (NIH-NIA), May 2006.

• “Hippocampal Stem/Progenitor Cells in Aging and Epilepsy” Invited Lecture, Epicenter, University of California, Irvine, April 2006.

• “Dentate Neurogenesis and Epilepsy” Invited Lecture, Department of Neuroscience, Rosalinda Franklin University School of Medicine (Chicago Medical School), Chicago. IL, May 2005.

• “Dentate Neurogenesis and Aging” Invited Lecture, National Neurotoxicology Program, US Environmental Protection Agency, Research Triangle Park, Durham, NC, March 2005.

• “Strategies to enhance dentate neurogenesis in the injured aged hippocampus” Invited Speaker, Symposium on STEM CELLS AND AGING, at Washington DC, sponsored by National Institute for Aging (NIH-NIA), November 2004.

• “Fetal neural cell transplantation therapy for temporal lobe epilepsy”, Invited Lecture, School of Veterinary Medicine, North Carolina State University, Raleigh, NC, January 2004.

• “Hippocampal injury does not increase the production of new neurons in the middle-aged and the senescent dentate gyrus” Invited Speaker, Symposium on STEM CELLS AND AGING, at Washington DC, sponsored by National Institute on Aging (NIH-NIA), May 2003.

• “Efficacy of Neural Transplants for Repair of the Injured Hippocampus in a Rat Model of Temporal Lobe Epilepsy”, Plenary Lecture, First Indo-US Symposium on Brain Research, New Delhi, INDIA; Sponsored by NIH-NIMH (USA) and National Brain Res. Center (INDIA), January 2002.

• “Proliferation and differentiation of rat hippocampal CA3 region stem cells”, Sensory Neuroscience Research Center, West Virginia University, Morgantown, West Virginia, USA, July 2001.

• “Prospects of Neural Grafting Therapy for Temporal Lobe Epilepsy”, Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, Kentucky. April 2001.

• “Hippocampal stem cells”, Invited lecture, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India, January 2000.

• “Epidermal growth factor responsive stem cells: survival, differentiation and neurite outgrowth in vitro”, INTERNATIONAL CONGRESS ON IN VITRO BIOLOGY, New Orleans, 1999.

• “Survival and dispersion of fetal hippocampal grafts following hippocampal kainate lesions”, Annual Meeting of American Society for Neural transplantation, Clear Water, 1994.

• “Integration and ultrastructure of nigral transplants grafted to anterior eye chamber, lateral ventricle and striatum of adult rats”, Dept. Neurosurgery, Duke Univ. Med. Ctr., Durham, NC, Feb. 1992.

• “Rapid aging of nigral transplants grafted to the striatum of young adult and adult rats”, Department of Neurology, University of Iowa, Iowa City, Iowa. March 1992.

• “Alterations in adrenal medulla and substantia nigra grafts following long-term survival in lateral ventricle and Striatum”, Department of Biology, Montana State University, Bozeman, Montana, Feb. 1991.

PROFESSIONAL AFFILIATIONS

Member, Society for Neuroscience, North America (SFN)

Charter Member, American Society for Neural Therapy & Repair (ASNTR)

Member, American Association for Advancement of Science (AAAS)

Member, American Epilepsy Society (AES)

Member, International Society for Stem Cell Research (ISSCR)

Member, International Society for Extracellular Vesicles (ISEV)

Fellow, American Society for Neural Therapy & Repair (ASNTR), Year of election: 1998.

Councilor, American Society for Neural Therapy & Repair (ASNTR), 2008-2011.

Number of Research Articles: 152 (125 as First or Senior author, and 27 as Co-author)

Number of Original Research Articles: 102 (86 as First or Senior author and 16 as Co-author)

Number of Reviews/Commentaries/Editorials: 50 (39 as First or Senior author and 11 as Co-author)

2020-2021

(1) Upadhya R, Madhu LN, Attaluri S, Gitai DLG, Pinson MR, Kodali M, Shetty G, Zanirati G, Kumar S, Shuai B, Weintraub ST, Shetty AK. Extracellular vesicles from human iPSC-derived neural stem cells: miRNA and protein signatures, and antiinflammatory and neurogenic properties. Journal of Extracellular Vesicles, 9: 1809064, 2020. [Published on August 26, 2020]

(2) Shetty AK, Attaluri S, Kodali M, Shuai B, Shetty GA, Upadhya D, Hattiangady B, Madhu LN, Upadhya R, Bates A, Rao X. Monosodium luminol reinstates redox homeostasis, improves cognition, mood and neurogenesis, and alleviates neuro- and systemic inflammation in a model of Gulf War Illness. Redox Biology 28:101389, 2020.

(3) Upadhya R, Zingg W, Shetty S, Shetty AK. Astrocyte-derived extracellular vesicles: Neuroreparative properties and role in the pathogenesis of neurodegenerative disorders. Journal of Controlled Release, 323:225-239, 2020.

(4) Shetty AK, Zanirati G. The interstitial system of the brain in health and disease. Aging Dis, 11:200-211, 2020.

(5) Kodali M, Castro OW, Kim DK, Thomas A, Shuai B, Attaluri S, Upadhya R, Gitai D, Madhu LN, Prockop DJ, Shetty AK. Intranasally Administered Human MSC-Derived Extracellular Vesicles Pervasively Incorporate into Neurons and Microglia in both Intact and Status Epilepticus Injured Forebrain. Int J Mol Sci. 21:181, 2020.

(6) Gitaí DLG, Dos Santos YDR, Upadhya R, Kodali M, Madhu LN, Shetty AK. Extracellular Vesicles in the Forebrain Display Reduced miR-346 and miR-331-3p in a Rat Model of Chronic Temporal Lobe Epilepsy. Mol Neurobiol. 57(3):1674-1687, 2020.

(7) Shetty AK. Mesenchymal Stem Cell Infusion Shows Promise for Combating Coronavirus (COVID-19)- Induced Pneumonia. Aging Dis 11(2):462-464, 2020.

(8) Upadhya D, Shetty AK. Promise of extracellular vesicles for diagnosis and treatment of epilepsy. Epilepsy & Behavior. Oct 18, 2019 [Epub ahead of print]; 106499, 2020.

(9) COVID-19 in India: Are biological and environmental factors helping to stem the incidence and severity? Chakrabarti SS, Kaur U, Banerjee A, Ganguly U, Banerjee T, Saha S, Parashar G, Prasad S, Chakrabarti S, Mittal A, Agrawal BK, Rawal RK, Zhao RC, Gambhir IS, Khanna R, Shetty AK, Jin K, Chakrabarti S. Aging Dis, 11(3):480-488, 2020.

2018-2019

(10) Upadhya D, Hattiangady B, Castro O, Shuai B, Kodali M, Attaluri S, Bates A, Dong Y, Zhang S-C, Prockop DJ, Shetty AK (2018): Human iPSC-derived MGE cell grafting after status epilepticus attenuates chronic epilepsy and co-morbidities via synaptic integration. Proceedings of the National Academy of Sciences (PNAS), USA. 116(1):287-296, 2019.

*Article highlighted in: “In this Issue” of PNAS, January 2, 2019 116 (1) 1-2; https://doi.org/10.1073/iti0119116
In the top 5% of all research outputs scored by Altmetric.

(11) Leite Góes Gitai D, de Andrade TG, Dos Santos YDR, Attaluri S, Shetty AK (2019) Chronobiology of Limbic Seizures: Potential Mechanisms and Prospects of Chronotherapy for Mesial Temporal Lobe Epilepsy. Neuroscience & Biobehavioral Reviews (98) 122-134, 2019.

(12) Hussain T, Kil H, Hattiangady B, Lee J, Kodali M, Shuai B, Attaluri S, Takata Y, Shen J, Abba MC, Shetty AK*, Aldaz CM (2019). Wwox deletion leads to reduced GABA-ergic inhibitory interneuron numbers and activation of microglia and astrocytes in mouse hippocampus. Neurobiology of Disease, 121:163-176. 2019.
*Co-Senior author.

(13) Mesraoua B, Deleu D, Kullmann DM, Shetty AK, Boon P, Perucca E, Mikati MA, Asadi-Pooya AA. Novel therapies for epilepsy in the pipeline. Epilepsy and Behavior. 97:282-290, 2019.

(14) Madhu LN, Attaluri S, Kodali M, Shuai B, Upadhya R, Gitai D, Shetty AK. Neuroinflammation in Gulf War Illness is linked with HMGB1 and complement activation, which can be discerned from brain-derived extracellular vesicles in the blood. Brain Behav Immun. 81:430-443, 2019.

(15) Upadhya D, Shetty AK. Extracellular Vesicles as Therapeutics for Brain Injury and Disease. Current Pharmaceutical Design, 25(33):3500-3505, 2019.

(16) Upadhya D, Kodali M, Gitai D, Castro OW, Zanirati G, Upadhya R, Attaluri S, Mitra E, Shuai B, Hattiangady B, Shetty AK. A Model of Chronic Temporal Lobe Epilepsy Presenting Constantly Rhythmic and Robust Spontaneous Seizures, Co-morbidities and Hippocampal Neuropathology. Aging Dis. 10(5):915-936, 2019. C

(17) Shetty AK, Upadhya R, Madhu LN, Kodali M. Novel Insights on Systemic and Brain Aging, Stroke, Amyotrophic Lateral Sclerosis, and Alzheimer's Disease. Aging Dis.;10(2):470-482, 2019.

(18) Kodali M, Hattiangady B, Shetty G, Bates A, Shuai B, Shetty AK (2018): Curcumin Treatment Leads to Better Cognitive and Mood Function in a Model of Gulf War Illness with Enhanced Neurogenesis, and Alleviation of Inflammation and Mitochondrial Dysfunction in the Hippocampus. Brain, Behavior and Immunity. 69:499-514, 2018.

(19) Shetty AK, Kodali M, Upadhya R, Madhu LN (2018): Emerging Anti-Aging Strategies - Scientific Basis and Efficacy. Aging & Disease 2018 Dec 4;9(6):1165-1184, 2018.

(20) Thery C, (plus 302 authors), Shetty AK, (plus 77 authors), Zuba-Surma EK (2018): Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. Journal of Extracellular Vesicles 7(1):1535750. doi: 10.1080/20013078.2018.1535750. eCollection 2018.

(21) Vogel A, Upadhya R, Shetty AK (2018) Neural stem cell derived extracellular vesicles: Attributes and prospects for treating neurodegenerative disorders. EBioMedicine 38:273-282, 2018

(22) Upadhya D, Castro, OW, Upadhya R, Shetty AK (2018): Prospects of Cannabidiol for Easing Status Epilepticus Induced Epileptogenesis and Related Co-morbidities. Molecular Neurobiology, 55:6956-6964, 2018

(23) Huang H, Young W, Chen L, Feng S, Zoubi ZMA, Sharma HS, Saberi H, Moviglia GA, He X, Muresanu DF, Sharma A, Otom A, Andrews RJ, Al-Zoubi A, Bryukhovetskiy AS, Chernykh ER, Domańska-Janik K, Jafar E, Johnson WE, Li Y, Li D, Luan Z, Mao G, Shetty AK, and 42 other authors (2018). Clinical Cell Therapy Guidelines for Neurorestoration (IANR/CANR 2017), Cell Transplant. 27:310-324, 2018

(24) Dos Santos JF, de Melo Bastos Cavalcante C, Barbosa FT, Gitaí DLG, Duzzioni M, Tilelli CQ, Shetty AK, de Castro OW (2018). Maternal, fetal and neonatal consequences associated with the use of crack cocaine during the gestational period: a systematic review and meta-analysis. Archives of Gynecology and Obstetrics, 2018 Sep;298(3):487-503. doi: 10.1007/s00404-018-4833-2. Epub Jun 27, 2018

(25) Petrescu AD, Grant S, Frampton G, McMillin M, Kain J, Kodali M, Shetty AK, Sharon DeMorrow (2018): Gulf war illness-related chemicals increase CD11b/c+ monocyte infiltration into the liver and aggravate hepatic cholestasis in a rodent model. Nature Scientific Reports, 2018 Sep 3;8(1):13147. doi: 10.1038/s41598-018-31599-9, 2018

(26) Matos HC, Koike BDV, Pereira WS, Andrade TG, Castro OW, Duzzioni M, Kodali M, Leite JP, Shetty AK*, Gitaí DLG (2018): Rhythms of core clock genes and Spontaneous Locomotor Activity in post-Status Epilepticus-model of Mesial Temporal Lobe Epilepsy. Frontiers in Neurology, 9:632, 2018
*Co-Senior author

(27) Kirmani BF, Shetty AK, Shapiro LA (2018): Editorial: New Directions in the Management of Status Epilepticus. Frontiers in Neurology. 9:994, 2018

2016-2017

(28) Long Q, Upadhya D, Hattiangady B, Kim DK, An SY, Shuai B, Prockop DJ, Shetty AK (2017) Intranasal MSC-derived A1-exosomes ease inflammation, and prevent abnormal neurogenesis and memory dysfunction after status epilepticus. Proceedings of the National Academy of Sciences (PNAS), USA. Apr 25;114(17): E3536-E3545, 2017. http://www.pnas.org/content/early/2017/04/05/1703920114.long

(29) Shetty G, Hattiangady B, Upadhya D, Bates A, Attaluri S, Shuai B, Kodali M, Shetty AK (2017) Chronic oxidative stress, mitochondrial dysfunction, Nrf-2 activation and inflammation in the hippocampus accompany heightened systemic inflammation and oxidative stress in Gulf war illness. Frontiers in Molecular Neuroscience, Jun 14;10:182. doi: 10.3389/fnmol.2017.00182. eCollection 2017. http://journal.frontiersin.org/article/10.3389/fnmol.2017.00182/full

(30) Emmerich T, Zakirova Z, Klimas N, Sullivan K, Shetty AK, Evans JE Ait-Ghezala G, Mullan M, Crynen G, Abdullah L, Crawford F (2017). Phospholipid profiling of plasma from GWI veterans and rodent models to identify potential biomarkers of Gulf war illness. PLoS One Apr 28;12(4): e0176634, 2017.
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176634

(31) Long Q, Luo Q, Wang K, Bates A, Shetty AK (2017): Mash1-dependent Notch Signaling Pathway Regulates GABA-ergic Neuron-Like Differentiation from Bone Marrow-Derived Mesenchymal Stem Cells. Aging and Disease, 8(3):301-313, 2017. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440110/

(32) Castro OW, Upadhya D, Kodali M and Shetty AK (2017) Resveratrol for Easing Status Epilepticus Induced Brain Injury, Inflammation, Epileptogenesis, and Cognitive and Memory Dysfunction—Are We There Yet? Front. Neurol. 8:603. doi:10.3389/fneur.2017.00603, 2017.

(33) Shetty AK, Hattiangady B: Grafted subventricular zone neural stem cells display robust engraftment and similar differentiation properties and form new neurogenic niches in the young and aged hippocampus. Stem Cells Translational Medicine, Sep;5(9):1204-15. doi: 10.5966/sctm.2015-0270., 2016.

(34) Kodali M, Megahed T, Mishra V, Shuai B, Hattiangady B, Shetty AK: Voluntary running exercise mediated enhanced neurogenesis does not obliterate retrograde spatial memory. Journal of Neuroscience, Aug 3;36(31):8112-22. doi: 10.1523/JNEUROSCI.0766-16, 2016. http://www.jneurosci.org/content/36/31/8112.long

(35) Upadhya D, Hattiangady B, Shetty GA, Zanirati G, Kodali M, Shetty AK: Neural stem cell or human induced pluripotent stem cell-derived GABA-ergic progenitor cell grafting in an animal model of chronic temporal lobe epilepsy. Current Protocols in Stem Cell Biology, Aug 17; 38: 2D.7.1-2D.7.47. doi: 10.1002/cpsc.9, 2016. https://www.ncbi.nlm.nih.gov/pubmed/27532817

(36) Shetty AK, Hattiangady B: Neural stem cells in the adult brain: Altered activity in aging, Alzheimer’s disease, mood disorders and epilepsy. Chapter for the book, Neural Cell Biology (C. Wang and W. Slikker, Eds), Taylor & Francis Group LLC, in press, 2016.

(37) Shetty AK, Upadhya D: GABA-ergic cell therapy for epilepsy: Advances, Limitations and Challenges. Neuroscience and Biobehavioral Reviews, 62:35-47, 2016.
https://www.ncbi.nlm.nih.gov/pubmed/26748379

(38) Kim DK, Nishida H, An SY, Shetty AK, Bartosh TJ, Prockop DJ. Chromatographically isolated CD63+CD81+ extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI. Proceedings of the National Academy of Sciences (PNAS), USA. 113: 170-175, 2016.
http://www.pnas.org/content/113/1/170.long

(39) Shetty AK, Bates A: Potential of GABA-ergic cell therapy for schizophrenia, neuropathic pain, and Alzheimer and Parkinson's diseases. Brain Res 1638 (Pt A): 74-87, 2016. https://www.ncbi.nlm.nih.gov/pubmed/26423935

2014-2015

(40) Mishra V, Shuai B, Kodali M, Shetty GA, Hattiangady B, Rao X, Shetty AK: Resveratrol treatment after status epilepticus restrains neurodegeneration and abnormal neurogenesis with suppression of oxidative stress and inflammation. Scientific Reports (Nature Publishing Group), 5:17807; Dec 7, 2015. http://www.nature.com/articles/srep17807

(41) Agadi S, Shetty AK: Prospects of Bone Marrow Mononuclear Cells and Mesenchymal Stem Cells for Treating Status Epilepticus and Chronic Epilepsy. Stem Cells, 33:2093-2103, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25851047

(42) Kodali M, Parihar V, Hattiangady B, Mishra V, Shuai B, Shetty AK: Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature, and reduced glial activation. Scientific Reports (Nature Publishing Group), 5:8075; Jan 28, 2015. http://www.nature.com/articles/srep08075

(43) Megahed T, Hattiangady B, Shuai B, Shetty AK: Parvalbumin and neuropeptide Y expressing hippocampal GABA-ergic interneuron numbers decline in a model of Gulf war illness. Frontiers in Cellular Neuroscience, 8:447, Jan 8, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25620912

(40) Shetty AK: Adult neural stem cells and brain homeostasis. Chapter for the book, Homeostatic Control of Brain Function (D. Boison an4 S. Masino, Eds), Oxford University Press, pp. 202-228, 2015.

(45) Shetty AK: Introduction to Neural Stem Cells in Health and Disease. Introduction chapter for the book, Neural Stem Cells in Health and Disease (A.K. Shetty, Ed), World Scientific Press, pp.1-20, 2015.

(46) Shetty AK, Hattiangady B: Neural stem cell therapy for easing status epilepticus induced hippocampus dysfunction and chronic temporal lobe epilepsy. Chapter for the book, Neural Stem Cells in Health and Disease (A.K. Shetty, Ed), World Scientific Press, pp.409-438, 2015.

(47) Shetty AK, Jin K: Neural stem cell activity and neurogenesis after stroke. Chapter for the book, Neural Stem Cells in Health and Disease (A.K. Shetty, Ed), World Scientific Press, pp.133-150, 2015.

(48) Shetty AK, Mishra V, Kodali M, Hattiangady B: Blood brain barrier dysfunction and delayed neurological deficits in mild traumatic brain injury induced by blast shock waves. Frontiers in Cellular Neuroscience, 8:232, Aug 13, 2014. http://www.ncbi.nlm.nih.gov/pubmed/25165433

(49) Hattiangady B, Mishra V, Kodali M, Shuai B, Rao, X, Shetty AK: Object location and object recognition memory impairments, motivation deficits and depression in a model of Gulf War illness. Frontiers in Behavioral Neuroscience, 8:78, March 13, 2014. doi: 10.3389/fnbeh.2014.00078. eCollection 2014. http://www.ncbi.nlm.nih.gov/pubmed/24659961

(50) Shetty AK: Hippocampal injury-induced cognitive and mood dysfunction, altered neurogenesis, and epilepsy: Can early neural stem cell grafting intervention provide protection? Epilepsy & Behavior, 38:117-2, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24433836

2012-2013

(51) Parihar VK, Hattiangady B, Shuai B, Shetty AK: Mood and memory deficits in a model of Gulf war illness are linked with reduced neurogenesis, partial neuron loss and mild inflammation in the hippocampus. Neuropsychopharmacology, 38: 2348-2362, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23807240

(52) Watanabe J. Shetty AK, Hattiangady B, Kim D-K, Foraker JE, Nishida H, Prockop DJ: Administration of TSG-6 improves memory after traumatic brain injury in mice. Neurobiology of Disease, 59:86-99, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23851308

(53) Shetty AK, Hattiangady B: Postnatal age governs the extent of differentiation of hippocampal CA1 and CA3 subfield neural stem/progenitor cells into neurons and oligodendrocytes. International Journal of Developmental Neuroscience, 31: 646-656, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23743166

(54) Shetty GA, Hattiangady B, Shetty AK: Neural stem cell- and neurogenesis-related gene expression profiles in the young and aged dentate gyrus. AGE, 35: 2165-2176, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23322452

(51) Shetty AK: Prospects of Levetiracetam as a neuroprotective drug against status epilepticus, traumatic brain injury and stroke. Fr5ntiers in Neurology, 4:172, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24204362

(57) Shetty AK, Hattiangady B, Rao MS, Shuai B: Neurogenesis response of middle-aged hippocampus to acute seizure activity. PLoS One, 7(8):e43286, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22912847

(58) Shetty AK: Neural stem cell therapy for temporal lobe epilepsy, In: Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012. http://www.ncbi.nlm.nih.gov/pubmed/22787648

2010-2011

(59) Parihar VK, Hattiangady B, Kuruba R, Shuai B, Shetty AK: Predictable chronic mild stress improves mood, hippocampal neurogenesis and memory. Molecular Psychiatry, 16, 171-183, 2011. http://www.ncbi.nlm.nih.gov/pubmed/20010892

(60) Hattiangady B, Shetty AK: Neural stem cell grafting in an animal model of chronic temporal lobe epilepsy. Current Protocols in Stem Cell Biology, Chapter 2, Unit2D.7, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21913169

(61) Hattiangady B, Kuruba R, Shetty AK: Acute seizures in old age leads to a greater Loss of CA1 pyramidal neurons, an increased propensity for developing chronic TLE and a severe cognitive dysfunction, Aging and Disease, 2:1-17, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21339903

(62) Kuruba R, Hattiangady B, Parihar VK, Shuai B, Shetty AK: Differential susceptibility of interneurons expressing neuropeptide y or parvalbumin in the aged hippocampus to acute seizure activity., PLoS ONE, 6 (9), e24493, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21915341

(63) Shetty AK, Hattiangady B, Rao MS, Shuai B: Deafferentation enhances neurogenesis in the young and middle-aged hippocampus but not in the aged hippocampus. Hippocampus, 21 (6), 631-46, 2011. http://www.ncbi.nlm.nih.gov/pubmed/20333732

(64) Shetty AK: Progress in Cell Grafting Therapy for Temporal Lobe Epilepsy. Neurotherapeutics, 8(4): 721-735, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21892793

(65) Shetty AK: Promise of resveratrol for easing status epilepticus and epilepsy. Pharmacology & Therapeutics, 131 (3), 269-86, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21554899

(66) Waldau B, Hattiangady B, Kuruba R, Shetty AK: Medial ganglionic eminence-derived neural stem cell grafts ease spontaneous seizures and restore GDNF expression in a rat model of chronic temporal lobe epilepsy. Stem Cells, 28, 1153-1164, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20506409
Cited by 122 articles

(67) Hattiangady B, Shetty AK: Decreased neuronal differentiation of newly generated cells underlies diminished neurogenesis in chronic temporal lobe epilepsy. Hippocampus, 20:97-112, 2010. http://www.ncbi.nlm.nih.gov/pubmed/19309040

(68) Shetty AK: Neural stem cell therapy for temporal lobe epilepsy, Epilepsia, 51 (s5): 92-92, 2010. http://onlinelibrary.wiley.com/doi/10.1111/j.1528-1167.2010.02878.x/full

(69) Shetty AK: Issues to ponder when correlating hippocampal neurogenesis with hippocampal-dependent memory function, Neurobiology of Aging, 31:2181-2184, 2010. Commentary http://www.ncbi.nlm.nih.gov/pubmed/20817352

(70) Shetty AK: Reelin signaling, hippocampal neurogenesis, and efficacy of aspirin intake & stem cell transplantation in aging and Alzheimer's disease, Aging and Disease, 1, 2-11, 2010. Review http://www.ncbi.nlm.nih.gov/pubmed/20953352

(71) Hattiangady B, Kuruba R, Shetty, AK. Effects of epileptic seizures on hippocampal neurogenesis, Chapter 14, in: Adult Neurogenesis and Central Nervous System Diseases, 2010 (Editor: K. Jin), ISBN: 978-81-7895-463-469, 2010. Book Chapter

(72) Jin K, Shetty AK, Greenberg D. Aging & Disease, a bridge between aging and age-related disease. Aging & Disease, 1:1, 2010. Editorial http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295020/

2008-2009

(73) Shetty AK, Hattiangady B, Rao MS: Vulnerability of hippocampal GABA-ergic interneurons to kainate induced excitotoxic injury during old age. Journal of Cellular & Molecular Medicine, 13(8B):2408-2423, 2009. http://www.ncbi.nlm.nih.gov/pubmed/20141618

(74) R. Kuruba, Hattiangady B, Shetty AK. Hippocampal neurogenesis and neural stem cells in chronic temporal lobe epilepsy Epilepsy & Behavior, 14 Suppl 1:65-73, 2009. Review, http://www.ncbi.nlm.nih.gov/pubmed/18796338

(75) Hattiangady B, Rao MS, Shetty AK: Grafting of Striatal Precursor Cells into Hippocampus Shortly after Status Epilepticus Restrains Chronic Temporal Lobe Epilepsy. Experimental Neurology. 212:468-481, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18579133

(76) Shetty AK, Rao MS, Hattiangady B: Behavior of Hippocampal Stem/Progenitor Cells Following Grafting into the Injured Aged Hippocampus. Journal of Neuroscience Research, 2008 86(14):3062-74. [Epub ahead of print] PMID: 18618674, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18618674

(77) Rao MS, Hattiangady B, Shetty AK: Status Epilepticus during old age is not associated with increased hippocampal neurogenesis. Hippocampus, 18:931-44, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18493929

(78) Hattiangady B, Rao MS, Shetty AK: Plasticity of hippocampal stem/progenitor cells to enhance neurogenesis in response to injury is lost by middle age, Aging Cell, 7:207-224. 2008. http://www.ncbi.nlm.nih.gov/pubmed/18241325

(79) Hattiangady B, Shetty AK: Aging Does not Alter the Number or Phenotype of Putative Stem/Progenitor Cells in the Neurogenic Region of the Hippocampus. Neurobiology of Aging, 29(1):129-47, 2008. http://www.ncbi.nlm.nih.gov/pubmed/17092610

(80) Waldau B, Shetty AK Behavior of Neural Stem Cells in the Alzheimer's Brain, Cellular and Molecular Life Sciences, 65:2372-84, 2008. Review, http://www.ncbi.nlm.nih.gov/pubmed/18500448

(81) Acharya M, Hattiangady B, Shetty AK. Progress in neuroprotective strategies for preventing epilepsy. Progress in Neurobiology, 84:363-404. 2008. Review, http://www.ncbi.nlm.nih.gov/pubmed/18207302

(82) Dhanushkodi A, Shetty AK. Is exposure to enriched environment beneficial for functional post-lesional recovery in TLE? Neuroscience and Biobehavioral Reviews, 32:657-674, 2008. Review, http://www.ncbi.nlm.nih.gov/pubmed/18178250

(83) Hattiangady B., Shetty AK. Implications of declined hippocampal neurogenesis in chronic temporal lobe epilepsy EPILEPSIA, 2008, 49 (s5) 26-41. Review, Review.
http://www.ncbi.nlm.nih.gov/pubmed/18522598

2006-2007

(84) Shetty AK, Hattiangady B: Restoration of calbindin after fetal hippocampal CA3 cell grafting into the injured hippocampus in a rat model of temporal lobe epilepsy. Hippocampus, 17(10): 943-956, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17604349

(85) Rai K, Hattiangady B, Shetty AK: Enhanced production and dendritic growth of new dentate granule cells in the middle-aged hippocampus following intracerebroventricular FGF-2 infusions. Eur J Neurosci, 26:1765-1779, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17883411

(86) Rao MS, Hattiangady B, Rai KS, Shetty AK: Strategies for enhanced survival and anti-epileptogenic effects of hippocampal fetal cell grafts in the hippocampus of rats exhibiting chronic temporal lobe epilepsy. Neurobiology of Disease, 27:117-132, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17618126

(87) Hattiangady B, Shuai B, Cai J, Coksaygan T, Rao MS, Shetty AK: Increased dentate neurogenesis after grafting of glial restricted progenitors or neural stem cells in the aging hippocampus STEM CELLS, 25:2104-2117, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17510219

(88) Shetty AK and Hattiangady B. Prospects of Stem Cell therapy for Temporal Lobe Epilepsy. Stem Cells, 25:2396-2407, 2007. Review, http://www.ncbi.nlm.nih.gov/pubmed/17600108

(89) R. Kuruba, Shetty AK. Could hippocampal neurogenesis be a future drug target for treating temporal lobe epilepsy? CNS and Neurodegenerative Disorders-Drug Targets, 6(5): 342-57, 2007. Review, http://www.ncbi.nlm.nih.gov/pubmed/18045163

(90) Rao MS, Hattiangady B, Shetty AK: The window and mechanisms of major age related decline in the production of new neurons within the dentate gyrus of the hippocampus. Aging Cell, 5:545-558, 2006. http://www.ncbi.nlm.nih.gov/pubmed/17129216

(91) Hattiangady B, Rao MS, Zaman V, Shetty AK: Incorporation of embryonic CA3 cell grafts into the adult hippocampus at 4-months after injury: effects of combined neurotrophic supplementation and caspase inhibition. Neuroscience, 139:1369-1383, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16580143

(92) Rao, MS, Hattiangady B, Reddy DS, Shetty AK: Hippocampal neurodegeneration, spontaneous seizures, and mossy fiber sprouting in the F344 rat model of temporal lobe epilepsy. Journal of Neuroscience Research, 83:1088-1105, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16493685

(93) Rao, MS, Hattiangady B, Shetty AK: Fetal hippocampal CA3 cell grafts enriched with FGF-2 and BDNF exhibit robust long-term survival and integration and suppress aberrant mossy fiber sprouting in the injured middle-aged hippocampus. Neurobiology of Disease, 21:276-290, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16099669

2004-2005

(94) Shetty AK, Zaman V, Hattiangady B: Repair of the injured adult hippocampus through graft-mediated modulation of the plasticity of the dentate gyrus in a rat model of temporal lobe epilepsy. Journal of Neuroscience, 25: 8391-8401, 2005.

(95) Shetty AK, Hattiangady B, Shetty GA: Stem/progenitor cell proliferation factors FGF-2, IGF-1, and VEGF exhibit early decline during the course of aging in the hippocampus: role of astrocytes, GLIA, 51:173-186, 2005.

(96) Hattiangady B, Rao MS, Shetty GA, Shetty AK: BDNF, p-CREB and NPY decline as early as middle age in the dentate gyrus and hippocampal CA1 and CA3 subfields. Experimental Neurology, 195:353-371. 2005.

(97) He J, Nixon K, Shetty AK, Crews FT: Chronic alcohol exposure reduces hippocampal neurogenesis and dendritic growth of newborn neurons. European Journal of Neuroscience, 21:2711-2720, 2005.

(98) Rao MS, Hattiangady B, Abdel-Rahman A, Stanley D, Shetty AK: Newly born cells in the aging dentate gyrus display normal migration, survival and neuronal fate-choice but endure retarded early maturation. European Journal of Neuroscience, 21: 464-476. 2005.

(99) Hattiangady B, Rao MS, Shetty AK. Chronic temporal lobe epilepsy severely diminishes dentate neurogenesis in the adult hippocampus. Neurobiology of Disease, 17: 473-490, 2004.

(100) Shetty AK, Rao MS, Hattiangady B, Zaman V, Shetty GA: Hippocampal neurotrophin levels after injury: Relationship to the age of the hippocampus at the time of injury. Journal of Neuroscience Research, 78:520-532, 2004.

(101) Shetty AK: Progenitor cells from the CA3 region of the E19 rat hippocampus generate region-specific neuronal phenotypes in vitro. Hippocampus, 14: 595-614, 2004.

(102) Rao MS, Shetty AK: Efficacy of doublecortin as a marker to analyze the absolute number and dendritic growth of newly generated neurons in the adult dentate gyrus. Eur. Journal of Neuroscience, 19: 234-246, 2004.

(103) Stanley DP, Shetty AK: Aging in the rat hippocampus is associated with widespread reductions in the number of glutamate decarboxylase-67 positive interneurons but not interneuron degeneration. Journal of Neurochemistry, 89: 204-216, 2004. Cited by 122 articles

(104) Abdel-Rahman, A, Rao MS, Shetty AK: Aging impairs the response of astrocytes to neurodegeneration and deafferentation in the hippocampus. GLIA, 47: 299-313, 2004.

(105) Safford KM, Safford SD, Gimble JM, Shetty, AK, Rice HE: Characterization of neuronal/glial differentiation of murine adult adipose-derived stromal cells. Experimental Neurology, 187:319-328, 2004.

(106) Abdel-Rahman A, Abou-Donia S, El-Masry E, Shetty AK, Abou-Donia M: Stress and combined exposure to low doses of pyridostigmine bromide, DEET, and permethrin produces neurochemical and neuropathological alterations in cerebral cortex, hippocampus and cerebellum. J Toxicol Environ Health A, 67:163-192, 2004.

(107) Pradhan A, Shetty AK, Turner, DA: Clinical prospects for neural grafting therapy for cortical lesions. Modern Neurosurgery (Editor: Turner DA), CRC Press, pp. 17-36, 2004.

(108) Shetty AK: Editorial: Stem cells and Aging. Aging Cell, 3:331-331, 2004.

2002-2003

(109) Shetty AK, Zaman V, Shetty G: Hippocampal neurotrophin levels in a kainate model of temporal lobe epilepsy: a lack of correlation between BDNF content and progression of aberrant dentate mossy fiber sprouting. Journal of Neurochemistry, 87: 147-159, 2003.

(110) Zaman V, Shetty AK: Pre-treatment of donor cells with FGF-2 enhances survival of fetal hippocampal CA3 cell transplants in the chronically lesioned young adult hippocampus. Experimental Neurology, 183: 11-24, 2003. Cover article

(111) Zaman, V, Shetty AK: Fetal hippocampal CA3 cell grafts enriched with FGF-2 exhibit enhanced neuronal integration into the lesioned aging hippocampus in a rat model of temporal lobe epilepsy. Hippocampus, 13: 618-632, 2003. Cited by 34 articles

(112) Guo-Ross SX, Jones KH, Shetty AK, Wilson WA, Swartzwelder HS. Prenatal dietary choline availability alters postnatal neurotoxic vulnerability in the adult rat. Neuroscience Letters, 341:161-163, 2003.

(113) Turner, DA, Shetty AK: Clinical Prospects for Neural Grafting Therapy for Hippocampal Lesions and Epilepsy. Neurosurgery, 52: 632-644, 2003. Review.

(114) Zaman, V, Shetty AK: Survival of fetal hippocampal CA3 cell grafts in the middle aged and aged hippocampus: Effect of host age and deafferentation. Journal of Neuroscience Research, 70: 190-199, 2002.

(115) Shetty AK: Entorhinal axons exhibit aberrant sprouting in CA1 subfield of the adult hippocampus after CA3-lesion. Hippocampus, 12: 534-542, 2002.

(116) Zaman, V, Shetty AK: Combined neurotrophic supplementation and caspase inhibition significantly enhances survival of fetal hippocampal CA3 cell grafts in kainic acid lesioned CA3 region of the aging hippocampus. Neuroscience, 109: 537-553, 2002.

(117) Guo-Ross, SX, Clark S, Montoya DAC, Jones KH, Obernier J, Shetty AK, White AM, Blusztajn JK, Wilson WA, Swartzwelder HS: Prenatal Choline Supplementation Protects Against Postnatal Neurotoxicity, Journal of Neuroscience, 22: RC195, 1-6, 2002.

(118) Abdel-Rahman, A, Shetty AK, Abou-Donia, MB: Acute exposure to sarin increases blood brain barrier permeability and induces neuropathological changes in the rat brain: dose response relationships. Neuroscience, 113: 721-741, 2002.

(119) Abdel-Rahman, A, Shetty AK, Abou-Donia, MB: Disruption of Blood Brain Barrier and Neuronal Cell Death in Cingulate Cortex, Dentate Gyrus, Thalamus, and Hypothalamus in A Rat Model of Gulf-War Syndrome. Neurobiology of Disease, 10: 306-326, 2002.

2000-2001

(120) Zaman V, Shetty AK: Fetal hippocampal CA3 cell grafts transplanted to lesioned CA3 region of adult hippocampus exhibit long-term survival in a rat model of temporal lobe epilepsy. Neurobiology of Disease, 8: 942-952, 2001.

(121) Shetty AK, Turner DA: Glutamic acid decarboxylase positive hippocampal interneurons undergo a permanent reduction in number following kainic acid induced destruction of CA3 pyramidal neurons. Experimental Neurology, 169: 276-297, 2001.

(122) Zaman V, Turner, DA, Shetty AK: Prolonged post-lesion transplantation delay adversely influences survival of both homotopic and heterotopic fetal hippocampal cell grafts in kainate-lesioned CA3 region of adult hippocampus. Cell Transplantation, 10: 41-52, 2001.

(123) Abdel-Rahman, A, Shetty AK, Abou-Donia MB: Subchronic derma application of N, N-diethyl m-toluamide (DEET) and permethrin to adult rats, alone or in combination, causes diffuse neuronal cell death and cytoskeletal abnormalities in the cerebral cortex and the hippocampus, and Purkinje neuron loss in the cerebellum. Experimental Neurology, 172: 153-171, 2001.

(124) Shetty AK and Turner DA: Fetal hippocampal transplants containing CA3 cells restore host hippocampal interneuron numbers in a rat model of temporal lobe epilepsy. Journal of Neuroscience, 20: 8788-8801, 2000.

(125) Shetty AK, Zaman V, and Turner DA: Pattern of long-distance projections from hippocampal field CA3 and CA1 cell grafts in lesioned CA3 of adult hippocampus follows intrinsic character of respective donor cells. Neuroscience, 99: 243-255, 2000.

(126) Zaman V, Turner DA and Shetty AK: Survival of grafted fetal neural cells in kainic acid lesioned CA3 region of adult hippocampus depends upon cell specificity. Experimental Neurology, 161:535-561, 2000.

1998-1999

(127) Shetty AK and Turner DA: Aging impairs axonal sprouting response of dentate granule cells following target loss. Journal of Comparative Neurology, 414: 238-254, 1999.

(128) Shetty AK and Turner DA: Vulnerability of dentate gyrus to aging and intracerebroventricular administration of kainic acid. Experimental Neurology, 158: 491-503, 1999.

(129) Shetty AK and Turner DA: Neurite Outgrowth from progeny of Epidermal growth factor-responsive hippocampal stem cells is significantly less robust than from fetal hippocampal cells following grafting onto organotypic slice cultures: Effect of brain-derived neurotrophic factor. Journal of Neurobiology, 38:391-413, 1999, Cover article.

(130) Shetty AK and Turner DA: In vitro survival and differentiation of neurons derived from epidermal growth factor-responsive postnatal hippocampal stem cells: enhancing and inducing effects of BDNF. Journal of Neurobiology, 35:395-425, 1998, Cover article

(131) Shetty AK and Turner DA: Hippocampal interneurons expressing glutamic acid decarboxylase and calcium binding proteins decrease with aging in Fischer 344 rats. Journal of Comparative Neurology 394:252-269, 1998.

1996-1997

(132) Shetty AK and Turner DA: Fetal hippocampal cells grafted to kainate-lesioned CA3 of adult hippocampus suppress aberrant supragranular sprouting. Experimental Neurology 143:231-245, 1997.

(133) Shetty AK and Turner DA: Development of long-distance efferent projections from fetal hippocampal grafts depends upon pathway specificity and graft location in kainate-lesioned adult hippocampus. Neuroscience 76:1205-1219, 1997.

(134) Shetty AK and Turner DA: Development of fetal hippocampal grafts in intact and lesioned hippocampus. Progress in Neurobiology 50:593-653, 1996. Review.

1994-1995

(135) Shetty AK and Turner DA: Enhanced cell survival in fetal hippocampal transplants grafted to adult rat hippocampus following kainate lesions. Neuroscience 67: 561-582, 1995.

(136) Shetty AK, Rapoza D, Madison RD and Turner DA: Selective laser-activated lesioning of pre-labeled fetal hippocampal grafts by intracellular photolytic chromophore. Neuroscience 69: 407-416, 1995.

(137) Shetty AK and Turner DA: Intracerebroventricular administration of kainic acid in rats causes alterations in hippocampal calbindin and non-phosphorylated neurofilament protein expression. Journal of Comparative Neurology 363: 581-599, 1995.

(138) Shetty AK and Turner DA: Non-phosphorylated neurofilament immunoreactivity in adult and developing hippocampus: application in grafting studies. Brain Research 676:293-306, 1995.

(139) Burrows RC, Shetty A K and Phillips DE: Effect of in utero ethanol exposure on the morphological development of the oculomotor nucleus in rat. Teratology 51:318-328, 1995.

(140) Clarke SR, Shetty AK, Bradley J and Turner DA: Reactive astrocytes express the embryonic intermediate neurofilament nestin. NeuroReport, 5:1885-1888, 1994.

(141) Shetty AK, Madison RD, Bradley J and Turner DA: Quantitative graft integration of fetal hippocampal transplants labeled with 5'bromodeoxy-uridine into normal hippocampus. Experimental Neurology 126:205-224, 1994.

(142) Shetty AK, Burrows RC, Wall KA and Phillips DE: Combined pre- and post-natal ethanol exposure alters the development of Bergmann glia in rat. International Journal of Developmental Neuroscience 12:641-649, 1994.

1992-1993

(143) Shetty AK, Burrows RC and Phillips DE: Alterations in neuronal development in the substantia nigra pars compacta following in utero ethanol exposure. Neuroscience 52:311-322, 1993.

(144) Shetty AK and Phillips DE: Effects of prenatal ethanol exposure on the development of Bergmann glia and astrocytes in the cerebellum: An immunohistochemical study. Journal of Comparative Neurology 321:19-32, 1992.

(145) Tandon PN, Kumar VM, Verma S, Gopinath G and Shetty AK: Fetal brain transplants in kainic acid lesioned caudate nucleus of adult rats. Journal of Neural Transplantation and Plasticity 3:125-134, 1992.

1990-1991

(146) Shetty AK, Banerjee R, Gopinath G and Tandon PN: Fetal nigra grafts in the anterior eye chamber of adult rats: A morphological study. Experimental Neurology 111:106-114, 1991.

(147) Shetty AK, Gopinath G and Tandon PN: Fetal nigra transplants in the lateral ventricle of adult rats: A long-term morphological study. Developmental Neuroscience 13:1-10, 1991.

(148) Shetty AK, Gopinath G and Tandon PN: Adrenal medullary autografts in the anterior eye chamber, lateral ventricle and striatum of adult rats: A long-term study. Journal of Neural Transplantation and Plasticity 2:175-191, 1991.

(149) Gopinath G, Shetty AK, and Tandon PN: Ageing changes in the transplants of fetal substantia nigra grafted to striatum of adult rat. Neuroscience 40:429-443, 1991.

(150) Gopinath G, Mahapatra AK, Bharadwaj JC, Banerjee R, Shetty AK, Sharma DN and Tandon PN: MPTP model of Parkinson's disease in monkey: Implications in neural transplantation. Proceedings of Indian National Science Academy 56:95-100, 1990. Review.

(151) Tandon PN, Gopinath G, Mahapatra AK and Shetty AK: Neural transplantation in mammals: Our experience. Proceedings of Indian National Science Academy 56:51-58, 1990. Review, Cited by 5 articles

(152) Gopinath G, Shetty AK, and Tandon PN: In oculo differentiation of fetal neocortex into retina in adult rat. In: Neurobiology of Sensory System, Plenum press, NY, pp.231-239, 1988. Book Chapter.

CITATIONS to Dr. SHETTY’s RESEARCH ARTICLES (entire period)

Source: Google Scholar, http://scholar.google.com/citations?user=LLZowc0AAAAJ&hl=en

Total Citations Received : 11177
h-index* : 56

i10-index** : 117
i100-index*** : 32

h-index*: h is the number of articles greater than h that have at least h citations. An h-index of 56 means that there are 56 articles in the list where each article has ≥56 citations.

i10-index**: An i10-index of 117 means that there are 117 articles in the list where each article has ≥10 citations.

i100-index***: An i100-index of 32 means that there are 32 articles in the list where each article has ≥100 citations.

EDITED BOOK:

Neural Stem Cells in Health & Disease, World Scientific Press, Editor, Ashok K. Shetty, 572 pp.
Released: October 2015 http://www.worldscientific.com/worldscibooks/10.1142/9309

(C) LINKS TO NEWS ARTICLES PERTAINING TO MY PUBLISHED PAPERS

(1) Hattiangady B, Rao MS, Shetty AK (2004). Chronic temporal lobe epilepsy is associated with severely declined dentate neurogenesis in the adult hippocampus. Neurobiology of Disease, 17(3):473-490.

Chronic Epilepsy Decreases Brain Cell Production in Critical Learning and Memory Center (Link: http://www.sciencedaily.com/releases/2005/01/050111174433.htm) SCIENCE DAILY, January 15, 2005.

Epilepsy Study Gives Insight to Mood Disorders by FOX NEWS
(Link: http://www.foxnews.com/story/0,2933,143449,00.html) January 5, 2005.

(2) Shetty AK, Hattiangady B, Shetty GA (2005). Stem/progenitor cell proliferation factors FGF-2, IGF-1, and VEGF exhibit early decline during the course of aging in the hippocampus: role of astrocytes. GLIA, 51(3):173-186.

New clues into the Aging Brain by DUKE UNIVERSITY news office
(Link: http://www.dukehealth.org/health_library/news/9191) August 5, 2005.

(3) Hattiangady B, Shetty AK (2006). Aging does not alter the number or phenotype of putative stem/progenitor cells in the neurogenic region of the hippocampus. Neurobiology of Aging 29:129-47.

Stem Cell Activity Deciphered in the Aging Brain by DUKE UNIVERSITY news office, December 18, 2006.

Stem Cell Activity Deciphered in the Aging Brain by SCIENCE DAILY, December 18, 2006.

Stem Cell Loss in Aging Brain may bring Poorer Memory by WASHINGTON POST, December 22, 2006

Old Age Memory Loss Explained by COSMOS magazine, Australia, December 20, 2006

(4) Hattiangady B, Shuai B, Cai J, Coksaygan T, Rao MS, Shetty AK: Increased dentate neurogenesis after grafting of glial restricted progenitors or neural stem cells in the aging hippocampus STEM CELLS, 25:2104-2117, 2007.

Novel way to trigger new neuron production in the aging brain by DUKEHEALTH.ORG (Link: http://www.dukehealth.org/health_library/news/10088) August 2007.

(5) Hattiangady B, Kuruba R, Shetty AK: Acute seizures in old age leads to a greater Loss of CA1 pyramidal neurons, an increased propensity for developing chronic TLE and a severe cognitive dysfunction, Aging and Disease, 2:1-17, 2011.

Outcome of acute seizures in more devastating in the aged population than in the young adults, SciGuru (http://www.sciguru.com/) Science News.

(6) Kuruba R, Hattiangady B, Parihar VK, Shuai B, Shetty AK: Differential susceptibility of interneurons expressing neuropeptide y or parvalbumin in the aged hippocampus to acute seizure activity., PLoS ONE, 6 (9), e24493, 2011.

Increased Vulnerability for Developing Temporal Lobe Epilepsy after Acute Seizure Activity in Old Age Explained, SciGuru (http://www.sciguru.com/) Science News.

(7) Hattiangady B, Shetty AK: Neural stem cell grafting counteracts hippocampal injury-mediated impairments in mood, memory and neurogenesis. Stem Cells Translational Medicine, 1:696-708, 2012.

Hippocampal Stem Cell Grafts Reportedly Improve Mood and Memory in Rats - in Neurology Today (October 2012); Stem Cell Therapy for Mood and Memory in STEM CELLS PORTAL (September 2012)

(8) Kodali M, Parihar V, Hattiangady B, Mishra V, Shuai B, Shetty AK: Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature, and reduced glial activation. Scientific Reports (Nature Publishing Group), 5:8075; Jan 28, 2015. http://www.nature.com/srep/2015/150128/srep08075/full/srep08075.html

Compound found in grapes, red wine may help prevent memory loss vital RECORD (Texas A&M HSC News), January 2015

Additional news links at:
http://www.altmetric.com/details.php?domain=www.nature.com&citation_id=3...

(9) Shetty AK, Hattiangady B: Grafted subventricular zone neural stem cells display robust engraftment and similar differentiation properties and form new neurogenic niches in the young and aged hippocampus. Stem Cells Translational Medicine, Sep;5(9):1204-15. doi: 10.5966/sctm.2015-0270., 2016.

News links:

(a) The Science Explorer: Neural Stem Cells May Have Potential to Regenerate Memory in Old Brains, Study Suggests
http://thescienceexplorer.com/brain-and-body/neural-stem-cells-may-have-...

(b) Science Daily: Regenerating memory with neural stem cells
https://www.sciencedaily.com/releases/2016/06/160614121902.htm

(c) RegMedNet: Could Neural Stem Cells Regenerate Memory in the aging Brain?
https://www.regmednet.com/users/13405-lauren-pulling/posts/7150-could-ne...

(10) Kodali M, Megahed T, Mishra V, Shuai B, Hattiangady B, Shetty AK: Voluntary running exercise mediated enhanced neurogenesis does not obliterate retrograde spatial memory. Journal of Neuroscience, Aug 3;36(31):8112-22. doi: 10.1523/JNEUROSCI.0766-16, 2016.

News links:

(a) Medical News Today: Exercise ‘Does not harm Memory” study confirms
http://www.medicalnewstoday.com/articles/312157.php

(b) The New York Times: Exercise Boosts Brain Health, but is There a Downside?
http://well.blogs.nytimes.com/2016/08/24/exercise-boosts-brain-health-bu...

(c) INSITE Magazine: Exercise & Neurogenesis: The Effects of Running on Memory
http://www.insitebrazosvalley.com/lifestyle/health-fitness/exercise-neur...

(11) Long Q, Upadhya D, Hattiangady B, Kim DK, An SY, Shuai B, Prockop DJ, Shetty AK. Intranasal MSC-derived A1-exosomes ease inflammation, and prevent abnormal neurogenesis and memory dysfunction after status epilepticus. Proceedings of the National Academy of Sciences (PNAS), USA. [Epub ahead of print] http://www.pnas.org/content/early/2017/04/05/1703920114.long Apr 10, 2017.

News Links:

(a) Preventing Seizure-Caused Damage to the Brain, VITALRECORD, Texas A&M University Health Science Center, College Station, TX, USA

(12) Upadhya D, Hattiangady B, Castro O, Shuai B, Kodali M, Attaluri S, Bates A, Dong Y, Zhang S-C, Prockop DJ, Shetty AK (2018): Human iPSC-derived MGE cell grafting after status epilepticus attenuates chronic epilepsy and co-morbidities via synaptic integration. Proceedings of the National Academy of Sciences (PNAS), USA. 116(1):287-296, 2019
https://www.pnas.org/content/116/1/287.long,

News Links:

(a) EUREKALERT (AAAS): https://www.eurekalert.org/pub_releases/2018-12/tau-scn122018.php

(b) VITALRECORD: Stem cell-derived neurons stop seizures, improve cognitive function

(c) DIGITAL TRENDS: Groundbreaking stem cell brain implant helps fight epilepsy in rats

CITATIONS TO MY RESEARCH PUBLICATIONS:

http://scholar.google.com/citations?hl=en&user=LLZowc0AAAAJ&pagesize=100...

PUBMED LINK TO MY PUBLICATIONS

http://www.ncbi.nlm.nih.gov/sites/myncbi/1DeDiyfOAQhQw/bibliography/4744...

Link to TAMU College of Medicine website:

https://medicine.tamu.edu/faculty/shetty.html